Application of bifidobacterium bifidum NX-7 in preparation of medicine for preventing or treating inflammatory diseases

The invention discloses application of bifidobacterium bifidum NX-7 in preparation of drugs for preventing or treating inflammatory diseases, and belongs to the technical field of microorganisms. According to the application of the bifidobacterium bifidum NX-7 in preparing the medicine for preventin...

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Hauptverfasser: LIU YAN, ZHANG ZHAO, ZHENG KANGDI
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention discloses application of bifidobacterium bifidum NX-7 in preparation of drugs for preventing or treating inflammatory diseases, and belongs to the technical field of microorganisms. According to the application of the bifidobacterium bifidum NX-7 in preparing the medicine for preventing or treating the inflammatory diseases, disclosed by the invention, the bifidobacterium bifidum NX-7 can inhibit neutrophil and macrophage from gathering towards the inflammation part of the tail fin of zebra fish in an in-vivo inflammation model; the bifidobacterium bifidum NX-7 can be used for inhibiting the increase of the content of LPS-induced inflammatory factors IL-1beta, IL-6 and TNF-alpha (Tumor Necrosis Factor-alpha); theoretical reference and guidance basis are provided for developing medicines for preventing or treating inflammatory diseases by utilizing the bifidobacterium bifidum NX-7. 本发明公开了两歧双歧杆菌NX-7在制备预防或治疗炎症性疾病药物中的应用,属于微生物技术领域。本发明公开的两歧双歧杆菌NX-7在制备预防或治疗炎症性疾病药物中的应用,两歧双歧杆菌NX-7在体内炎症模型中,能够抑制中性粒细胞和巨噬细胞往