Transdermal drug delivery preparation of antihistamine antiallergic drug and preparation method of transdermal drug delivery preparation

The invention discloses a transdermal drug delivery preparation of an antihistamine antiallergic drug and a preparation method of the transdermal drug delivery preparation, and relates to the technical field of biological medicines. The transdermal drug delivery preparation is composed of a drug sto...

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Bibliographische Detailangaben
Hauptverfasser: JIANG CHANGZHAO, PAN ZHEYAN, JIANG XIUMEI, FANG RENHUA, YE JINCUI
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention discloses a transdermal drug delivery preparation of an antihistamine antiallergic drug and a preparation method of the transdermal drug delivery preparation, and relates to the technical field of biological medicines. The transdermal drug delivery preparation is composed of a drug storage and a drug carrying matrix. The drug storage comprises the following components in percentage by weight: 1-12% of histamine antiallergic drugs, 5-35% of a penetration enhancer, 20-40% of an emulsifier, 30-40% of a drug solvent and 0.5-3% of a drug stabilizer; the drug-loaded matrix comprises the following components in percentage by weight: 20-25% of ester, 5-10% of a cross-linking agent, 20-30% of a high-molecular polymer and 35-55% of a solvent; the mass ratio of the transdermal drug delivery preparation drug storage to the drug loading matrix is (2: 5)-(3: 10). The transdermal drug delivery preparation has the quick-drying characteristic, can quickly form a hydrophobic membrane on the skin after being appli