Collagen hydroxyapatite composite biomimetic biological membrane and preparation method thereof

The invention relates to the technical field of biomedical materials, in particular to a collagen hydroxyapatite composite biomimetic biofilm and a preparation method thereof.The preparation method of the collagen hydroxyapatite composite biomimetic biofilm comprises the steps that type I collagen is dissolved in an acid solution, and a collagen solution is prepared; preparing a collagen and hydroxyapatite precursor mixed solution based on the collagen solution; preparing a collagen and hydroxyapatite suspension based on the collagen and hydroxyapatite precursor mixed solution; preparing a collagen hydroxyapatite composite material biological membrane based on collagen and hydroxyapatite suspension; after the product disclosed by the invention is prepared into a scaffold, the scaffold has a large-pore microstructure and is convenient for adhesion and proliferation of cells, so that the problems that the existing bone tissue engineering scaffold is low in porosity and inconvenient for adhesion and proliferatio