Hypotensive sea cucumber peptide as well as preparation method and application thereof

The invention discloses antihypertensive sea cucumber peptide and a preparation method and application thereof, and the method comprises the following steps: adding water into sea cucumbers, and homogenizing to obtain sea cucumber homogenate; adding neutral protease and trypsin into the sea cucumber homogenate for enzymolysis, centrifuging, and taking supernate; performing ultrafiltration on the supernate, and collecting the sea cucumber peptide with the molecular weight of less than or equal to 1000Da; the sea cucumber peptide with the molecular weight smaller than or equal to 1000 Da passes through a SephadexG-15 gel chromatographic column, purification and separation are conducted through RP-C18 reversed-phase high-performance liquid chromatography, and the sea cucumber peptide with the blood pressure reducing function is obtained. The content purity of the polypeptide prepared by the method is higher than 80% and is far higher than the content of polypeptide extracted by related technologies, so that the