Polypeptide and application thereof

The invention discloses a polypeptide and application thereof, and belongs to the technical field of biological medicine. The invention finds that the polypeptide N11 is low in expression in a psoriasis patient, can be used as a marker for psoriasis diagnosis and/or prognosis evaluation, further can...

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Bibliographische Detailangaben
Hauptverfasser:	SHI JUNFANG, CHEN JUNFAN, XIE YUYI, TAN YACHAO
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	HUMAN NECESSITIES HYGIENE INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEDICAL OR VETERINARY SCIENCE PHYSICS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS TESTING
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Beschreibung
Zusammenfassung:	The invention discloses a polypeptide and application thereof, and belongs to the technical field of biological medicine. The invention finds that the polypeptide N11 is low in expression in a psoriasis patient, can be used as a marker for psoriasis diagnosis and/or prognosis evaluation, further can be used as a detection target of a related kit and a detection method, and can be applied to preparation of a kit or a detection reagent for psoriasis diagnosis, risk evaluation or prognosis evaluation; in addition, the invention finds that the polypeptide N11 can be applied to preparation of drugs for preventing and/or treating psoriasis, when the polypeptide N11 is used as a drug, the occurrence of psoriasis can be inhibited through a Notch signal channel, psoriasis inflammation can be obviously relieved, expression of cytokines in skin inflammation can be inhibited, a new way is provided for treating psoriasis, and the polypeptide N11 can be used as the drug for preventing and/or treating psoriasis. The medicin