Prebiotic oral care compositions and methods

The present disclosure relates to a method of enhancing beneficial oral bacteria and reducing harmful oral bacteria, the method comprising administering an oral care composition comprising a sugar prebiotic, e.g., selected from the group consisting of hemolysin, N-acetyl-D-glucosamine, alpha-D-lactose, D-(+)-trehalose or D-(+)-raffinose, and mixtures thereof; and oral care compositions for use in such methods. The disclosure also relates to methods of using the prebiotic oral care compositions, screening methods, and methods of making. 本公开涉及增强有益口腔细菌和减少有害口腔细菌的方法，该方法包括施用口腔护理组合物，所述口腔护理组合物包含糖益生元，例如选自溶血素、N-乙酰基-D-葡糖胺、α-D-乳糖、D-(+)-海藻糖或D-(+)-棉子糖及其混合物；以及用于此类方法的口腔护理组合物。本公开还涉及使用益生元口腔护理组合物的方法、筛选方法和制备方法。