Method for rapidly determining 33 pesticide and metabolite residues in Qu fructus aurantii

The invention relates to the technical field of pesticide and metabolite residue detection in agricultural products, in particular to a method for rapidly determining 33 pesticide and metabolite residues in Qu fructus aurantii. According to the method, after a sample is extracted and purified by an improved QuEChERS method, GC-MS/MS analysis is performed in a multi-reaction monitoring (MRM) mode, and quantification is performed by an internal standard method. Under the optimized experiment condition, the linear relation of 33 determination substances in the range of 0.01-0.5 mg/L is good, and the limit of quantitation (LOQ) of the method is 0.02-0.1 mg/kg; under the standard addition levels of LOQ, 2.5 times of LOQ and 5 times of LOQ, the average recovery rates of other pesticides and metabolites except for phosphorus uptake-O and phosphorus uptake-S are all larger than 60%, and the relative standard deviation (RSD) is smaller than 17%. The method is simple and rapid in sample pretreatment, accurate in result