2-(5-fluoro-2, 4-dioxo-3, 4-dihydropyrimidine-1 (2H)-yl)-N-aryl acetamide derivative as well as preparation method and application thereof

The invention relates to a 2-(5-fluoro-2, 4-dioxo-3, 4-dihydropyrimidine-1 (2H)-yl)-N-aryl acetamide derivative as shown in a chemical structural formula I, a pharmaceutically acceptable salt of the derivative, a pharmaceutical composition of the derivative and an application of the derivative in preparation of antitumor drugs, r is selected from a group consisting of a methoxy group, a dimethoxy group, a trimethoxy group, a 2-hydroxy-3-methoxy group, a 2-hydroxy-4-methoxy group, a 2-hydroxy-5-methoxy group, a 2-hydroxy-6-methoxy group, a 3-hydroxy-2-methoxy group, a 3-hydroxy-4-methoxy group, a 3-hydroxy-5-methoxy group, a 3-hydroxy-6-methoxy group, a 4-hydroxy-2-methoxy group, a 4-hydroxy-3-methoxy group, a 4-hydroxy-3-methoxy group, a 4-hydroxy-4-methoxy group, a 4-hydroxy-4-methoxy group, a 4-hydroxy-4-methoxy group, a 4-hydroxy-4-methoxy group, a 4-hydroxy-4-methoxy group, a 4-hydroxy-4-methoxy group, a 4-hydroxy-4-methoxy group, a 4-hydroxy-4-methoxy group, a 4-hydroxy-4- the compound is selected from t