Induced differentiation system for promoting hematopoietic stem cells or hematopoietic progenitor cells to be differentiated into red blood cells and application thereof

The invention discloses an induced differentiation system for promoting hematopoietic stem cells or hematopoietic progenitor cells to be differentiated into erythrocytes and application thereof, and the induced differentiation system is suitable for induced differentiation of hematopoietic stem cell...

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Bibliographische Detailangaben
Hauptverfasser: DU RULONG, HUANG WENJING, ZHANG CHENGZHI, YU LEI, GU YUCHUN, GAO HUALEI, WU XUENING, WU LIDA
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention discloses an induced differentiation system for promoting hematopoietic stem cells or hematopoietic progenitor cells to be differentiated into erythrocytes and application thereof, and the induced differentiation system is suitable for induced differentiation of hematopoietic stem cells or hematopoietic progenitor cells from various sources into erythrocytes. The method has the advantages of high induced differentiation efficiency, strong stability, clear culture system components, high safety and the like, provides a red blood cell substitute for solving blood-source tension and preventing the transmission of blood-source diseases, and has huge market value and wide application prospect. 本发明公开了一种促进造血干细胞或造血祖细胞分化为红细胞的诱导分化体系及其应用,所述诱导分化体系适用于各种来源的造血干细胞或造血祖细胞向红细胞的诱导分化,具有诱导分化效率高、稳定性强、培养体系成分明确、安全性高等优点,为解决血源紧张及防止血源性疾病的传播提供了红细胞替代品,具有巨大的市场价值及广阔的应用前景。