Breviscapine nanoparticles and preparation method thereof

The invention provides a breviscapine nanosuspension and dried nanoparticle powder thereof. The preparation method is simple, convenient and efficient, does not need special process and equipment, is low in cost and is easy to industrialize. The breviscapine nanoparticles prepared by the invention are simple in formula, high in drug loading capacity and good in stability, the solubility and the dissolution rate of the breviscapine nanoparticles are remarkably improved, and the breviscapine nanoparticles are beneficial to further preparation forming and bioavailability improvement. 本发明提供了一种灯盏花素纳米混悬液及其干燥后的纳米粒粉末，其制法简便高效、无需特殊工艺和设备，成本低廉、易于产业化。本发明制得的灯盏花素纳米粒，其不仅配方简单、载药量高、稳定性良好，而且其溶解度和溶出度均得到显著改善，有利于进一步制剂成型并提高生物利用度。