Inhalable therapeutic agents

Compositions and methods of use thereof are described herein. The composition comprises a first population of inhalable particles and a second population of inhalable particles wherein the first inhalable particle comprises a first mucolytic agent contained within a first biodegradable capsule, and the second population of inhalable particles comprises the first mucolytic agent or a second mucolytic agent contained within a second biodegradable capsule. 本文描述了组合物及其使用方法。所述组合物包含第一可吸入颗粒群和第二可吸入颗粒群，其中所述第一可吸入颗粒包含含在第一可生物降解包囊内的第一粘液溶解剂，并且所述第二可吸入颗粒群包含含在第二可生物降解包囊内的所述第一粘液溶解剂或第二粘液溶解剂。