1, 2, 3, 4-tetrahydro-beta-carboline compound containing alkyl or aryl, composition, preparation method and application

The invention provides a 1, 2, 3, 4-tetrahydro-beta-carboline compound containing alkyl or aryl, a composition, a preparation method and application, and belongs to the technical field of medicinal chemistry. On the basis of tryptamine, various aldehyde or ketone fragments are introduced into the sy...

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Hauptverfasser: ZHOU YA, LIU LIWEI, ZHOU XIANG, SU SHANSHAN, WANG GUOQING, WU ZHIBING, YANG SONG, SUN ZHAOJU, XUE WEI
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention provides a 1, 2, 3, 4-tetrahydro-beta-carboline compound containing alkyl or aryl, a composition, a preparation method and application, and belongs to the technical field of medicinal chemistry. On the basis of tryptamine, various aldehyde or ketone fragments are introduced into the system, a series of 1, 2, 3, 4-tetrahydro-beta-carboline compounds containing alkyl or aryl structures are synthesized, and the compounds have excellent inhibition effects on plant pathogenic bacteria such as Xanthomonas oryzae pv. Oryzae, Xanthomonas citri pv. Citri and Xanthomonas syringae pv. Kiwifruit; the series of compounds have excellent prevention and treatment effects on plant pathogenic fungi such as botryosphaeria dothidea, rhizoctonia solani, pepper fusarium wilt, eggplant verticillium wilt, wheat scab and the like, and an important scientific basis is provided for research, development and creation of new pesticides. 本发明提供了一种含烷基或芳基的1,2,3,4-四氢-β-咔啉类化合物、组合物、制备方法和应用,属于药物化学技术领域。本发明以色胺为基础,将各种醛或酮片段引入到此体系中,合成一系