Short peptide extracted from herba epimedii and application of short peptide in promoting bone growth

According to the herba epimedii extracted oligopeptide and the application thereof in promoting bone growth, the oligopeptide in the traditional Chinese medicinal material herba epimedii is extracted and analyzed, the mechanism of the oligopeptide for improving bone related diseases is analyzed, and it is found that the oligopeptide with the sequence being VPIVMHDYLTGGFTANTSL can promote osteoblast proliferation by activating a phosphorylation pathway of MAPK, so that the bone growth is promoted, and the bone growth is promoted. And a certain foundation is laid for researching novel medicines for improving bone-related diseases. 本发明一种淫羊藿提取短肽及其在促进骨生长中的应用通过提取分析传统中药材淫羊藿中的短肽，分析其对于改善骨相关疾病的机理，发现序列为VPIVMHDYLTGGFTANTSL的短肽可以通过激活MAPK的磷酸化途径，促进成骨细胞的增殖，为研究新型的改善骨相关疾病的药物奠定了一定基础。