Acetylcysteine injection and preparation method thereof
The invention relates to the technical field of pharmaceutical preparations, and particularly discloses an acetylcysteine injection and a preparation method thereof. Comprising the following steps: adding water for injection accounting for 40-70% of the total preparation volume and disodium edetate...
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Format: | Patent |
Sprache: | chi ; eng |
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Zusammenfassung: | The invention relates to the technical field of pharmaceutical preparations, and particularly discloses an acetylcysteine injection and a preparation method thereof. Comprising the following steps: adding water for injection accounting for 40-70% of the total preparation volume and disodium edetate accounting for the prescription dosage into a preparation tank, uniformly mixing to obtain a disodium edetate solution, then adding acetylcysteine accounting for the prescription dosage, stirring and dissolving, then adjusting the pH value to 6.8-7.2, supplementing the water for injection to the total preparation volume to obtain acetylcysteine liquid medicine, and filling the acetylcysteine liquid medicine with the injection water. Then filtering through a multi-stage polyether sulfone filter element of which the pore diameter is sequentially reduced, filling nitrogen, controlling the headspace residual oxygen content in a filling container to be less than 3% after filling, sealing, sterilizing, carrying out lamp |
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