Inhalation IL-1 block treatment for respiratory tract immunopathology

Inhalation IL-1 block treatment for respiratory tract immunopathology

The present invention relates to a method of treating a lower airway inflammatory disease in a human subject in need thereof, comprising administering an effective amount of a recombinant human IL-1 receptor antagonist (rhIL-1Ra) directly to the lower airway of the human subject; wherein the inflamm...

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Hauptverfasser: CRYTZER KURTIS R, BARANOWSKI LUKE A, PALACIOS MANUEL, REINING SCOTT A
Format: Patent
Sprache:chi ; eng
Schlagworte:
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:The present invention relates to a method of treating a lower airway inflammatory disease in a human subject in need thereof, comprising administering an effective amount of a recombinant human IL-1 receptor antagonist (rhIL-1Ra) directly to the lower airway of the human subject; wherein the inflammatory disease is caused by coronavirus infection. 本发明涉及一种治疗有需要的人类受试者的下气道炎性疾病的方法，包括将有效量的重组人IL-1受体拮抗剂(rhIL-1Ra)直接施用至所述人类受试者的下气道；其中所述炎性疾病是由冠状病毒感染引起的。