Content determination and fingerprint spectrum construction method for multiple components in blood stasis arthralgia preparation

The invention relates to the field of traditional Chinese medicine analysis, in particular to a method for determining the content of multiple components in a blood stasis arthralgia preparation and constructing a fingerprint spectrum. According to the method, 5-hydroxymethylfurfural, tanshinol, chl...

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Bibliographische Detailangaben
Hauptverfasser: DONG XUEYUAN, WU YONGJUN, WANG YUEFEI, ZHOU CHUNLING, QU YANG, ZHOU SHUFAN
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention relates to the field of traditional Chinese medicine analysis, in particular to a method for determining the content of multiple components in a blood stasis arthralgia preparation and constructing a fingerprint spectrum. According to the method, 5-hydroxymethylfurfural, tanshinol, chlorogenic acid, ferulic acid, isochlorogenic acid B, rosmarinic acid, salvianolic acid B, salvianolic acid A, dihydrotanshinone I, cryptotanshinone, tanshinone IIA and 3-acetyl-11-keto-beta-boswellic acid are taken as index components, and content determination and fingerprint spectrum construction are carried out by adopting an ultra-high performance liquid chromatography. The method provided by the invention can simply, quickly and accurately determine the contents of the 12 components in the blood stasis arthralgia preparation, is good in accuracy, high in sensitivity and good in stability, can be used for more comprehensive quality control of the blood stasis arthralgia preparation, and can be used for construct