Preparation method of amorphous apattamide

The invention discloses a preparation method of amorphous apattamide, which comprises the following steps: (1) adding a compound I into an alcohol solution of methylamine, and reacting for 18-30 hours at-15-0 DEG C; (2) after the reaction is finished, adding an organic solvent and an acidic quenchin...

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Bibliographische Detailangaben
Hauptverfasser: HONG QING, LIANG JINQIAN, CHU DINGJUN, CHE FENGFENG, CHU LITAO
Format: Patent
Sprache:chi ; eng
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