Synthetic method and application of aurone derivatives with non-alcoholic steatohepatitis resistance

The invention discloses an aurone derivative with resistance to non-alcoholic steatohepatitis as well as a synthesis method and application of the aurone derivative, the structural general formula of the aurone derivative is shown in the specification, the synthesized aurone derivative is a new compound through spectrum and mass spectrum data analysis, and in-vitro cell activity research proves that the aurone derivative has a good application prospect. The aurone derivative provided by the invention is a compound with low toxicity and good non-alcoholic steatohepatitis resistance activity, and can be used for preparing medicines and functional foods for treating or preventing the non-alcoholic steatohepatitis. 本发明公开了一类具有抗非酒精性脂肪肝炎的橙酮类衍生物、合成方法及其应用，其结构通式为通过波谱和质谱数据分析表明合成得到的一类橙酮类衍生物为新化合物，且经体外细胞活性研究证明，本发明提供的一类橙酮类衍生物是一类低毒的、具有良好抗非酒精性脂肪肝炎活性的化合物，可制备治疗或预防非酒精性脂肪肝药物和功能性食品。