Balloon catheter with microneedle and preparation method thereof

The catheter comprises a catheter body, a balloon and the drug-loaded microneedle, the balloon is connected to the far end of the catheter body, a buffer layer is arranged on the peripheral face of the balloon, the drug-loaded microneedle is embedded in the buffer layer, and when the buffer layer is...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: GU MENGMENG, WANG SHENG, GUAN LIJUAN, WANG YONGGANG, DING YUNYU, DONG SHUHENG
Format: Patent
Sprache:chi ; eng
Schlagworte:
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Beschreibung
Zusammenfassung:The catheter comprises a catheter body, a balloon and the drug-loaded microneedle, the balloon is connected to the far end of the catheter body, a buffer layer is arranged on the peripheral face of the balloon, the drug-loaded microneedle is embedded in the buffer layer, and when the buffer layer is not pressed or the pressed pressure is smaller than a set value, the drug-loaded microneedle is inserted into the buffer layer. All the drug-loaded microneedles are positioned in the buffer layer; the method comprises the steps that the buffer layer is pressed down from the tip end of the drug-loaded microneedle, the plane end of the drug-loaded microneedle is blown, the drug-loaded microneedle completely enters the buffer layer, the buffer layer is attached to the surface of the balloon, and the balloon is folded with the pressure smaller than 4.5 atm. The balloon is small in size after being folded, extra equipment and technology do not need to be developed during folding, and the balloon has great market value;