3D printing piezoelectric bone repair scaffold based on shape memory polymer and preparation method thereof

The invention discloses a 3D printing piezoelectric bone repair scaffold based on a shape memory polymer and a preparation method thereof, and the preparation method comprises the following steps: adding barium titanate into a dopamine hydrochloride solution, stirring, adding a silane coupling agent...

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Hauptverfasser: CHEN SHILU, LI GUANLIN, HAN RUIJIA, ZHAO ZHENG, MIN YAJUN
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention discloses a 3D printing piezoelectric bone repair scaffold based on a shape memory polymer and a preparation method thereof, and the preparation method comprises the following steps: adding barium titanate into a dopamine hydrochloride solution, stirring, adding a silane coupling agent, and after the reaction is completed, adding barium titanate into a silver ammonia solution to prepare modified barium titanate nanoparticles; adding the modified barium titanate nanoparticles into epoxidized soybean oil acrylate, and adding a diluent and a photoinitiator to obtain photocuring slurry; and preparing the bone repair scaffold with piezoelectric effect and shape memory function from the obtained photocuring slurry through a photocuring 3D printer. According to the invention, the piezoelectric material can be excited through ultrasonic stimulation or autologous movement of an implanted part, so that micro-current is generated to promote bone regeneration; meanwhile, the shape memory material has the ad