Microbial culture medium optimization method and system based on correlation coefficient significance analysis

The invention discloses a microorganism culture medium optimization method and system based on correlation coefficient significance analysis, and relates to the technical field of multivariate statistics. The method comprises the following steps: constructing a PLSR full model of each response varia...

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Hauptverfasser: YANG XUEYI, NIE MIN, ZHU LING, HU XIUXIU, ZHU XINSHU, ZHANG MIAO, ZHAO WENHUI
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention discloses a microorganism culture medium optimization method and system based on correlation coefficient significance analysis, and relates to the technical field of multivariate statistics. The method comprises the following steps: constructing a PLSR full model of each response variable according to each experimental sample obtained by performing a uniform experiment by taking a culture medium component as an independent variable and an experimental product as the response variable; processing the PLSR full model to obtain a Pearson's correlation coefficient matrix between an independent variable and a response variable; adopting a t test method to obtain t test p values of the independent variable and the response variable according to the Pearson's correlation coefficient matrix; obtaining a saliency independent variable according to the p value detected by t; according to the experimental sample and the saliency independent variable, constructing a PLSR selection model of the response varia