Mutant of ELBD targeting peptide and application
The invention discloses a mutant of an ELBD targeting peptide and application of the mutant. The amino acid sequence of the mutant of the ELBD targeting peptide is shown as SEQ ID NO: 1, SEQ ID NO: 2 or SEQ ID NO: 3. The ELBD targeting peptide and the mutant thereof can be applied to various scenes...
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Format: | Patent |
Sprache: | chi ; eng |
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Zusammenfassung: | The invention discloses a mutant of an ELBD targeting peptide and application of the mutant. The amino acid sequence of the mutant of the ELBD targeting peptide is shown as SEQ ID NO: 1, SEQ ID NO: 2 or SEQ ID NO: 3. The ELBD targeting peptide and the mutant thereof can be applied to various scenes such as disease diagnosis, therapeutic drugs, directional delivery, directional degradation elimination and the like, can be developed into targeted therapeutic drugs, and can be used for treating related diseases. The targeting peptide is introduced into the nano antibody, so that the nano antibody has multi-target binding property and is suitable for more clinical application scenes. The targeting peptide is fused with the dsRBD, so that RNA molecules for treatment can be directionally delivered into specific target cells, the biological functions of the cells are influenced, and various diseases are treated. After the targeting peptide is coupled with the IgG binding structural domain, target molecules originall |
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