Preparation method of oseltamivir process impurity

The invention relates to preparation of an oseltamivir process impurity II. According to the method, raw materials for synthesis reaction are easy to obtain, reaction conditions are mild, operation is easy to control, the raw materials are safe and reliable, use of toxic substances is avoided, and a...

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Bibliographische Detailangaben
Hauptverfasser: CHEN YULIN, TIAN JIALIN, ZHANG YAN, ZHANG JIANGUO, MEI LIANGHE, SHI RENREN, ZENG JIE, WANG TONGGUI
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention relates to preparation of an oseltamivir process impurity II. According to the method, raw materials for synthesis reaction are easy to obtain, reaction conditions are mild, operation is easy to control, the raw materials are safe and reliable, use of toxic substances is avoided, and a foundation can be laid for later-stage industrial large-scale production. Meanwhile, the preparation method disclosed by the invention is high in reaction yield, and the obtained product is high in purity. 本公开涉及一种奥司他韦工艺杂质II的制备,所述方法合成反应原料易得,反应条件温和、操作容易控制、原料安全可靠,避免有毒物质的使用,能够为后期工业化放大生产奠定基础。同时本公开的制备方法反应收率高,所获得的产物纯度高。