Method and device for continuously synthesizing trientine hydrochloride and intermediate thereof

The invention relates to a method and a device for continuously synthesizing trientine hydrochloride and intermediates thereof, and the method comprises the following steps: preparing triethylene tetramine from ethylenediamine and 1, 2-dichloroethane under a solvent-free condition, and salifying to obtain the trientine hydrochloride. According to the method, in the first step, an organic solvent is not used, generation of by-products is avoided, materials in the reaction kettle can be discharged, anhydrous ethylenediamine can be continuously supplemented, the purpose of continuous production is achieved, ethylenediamine and triethylene tetramine can be recycled, raw materials are saved, and the cost is reduced. 本发明涉及一种连续合成盐酸曲恩汀及其中间体的方法和装置，该方法包括乙二胺和1,2-二氯乙烷在无溶剂条件下制备得到三乙烯四胺，再成盐得到盐酸曲恩汀。该方法第一步避免使用有机溶剂，避免副产物的产生，反应釜内的物料可以放出和持续补加无水乙二胺，实现连续生产的目的，乙二胺和三乙烯四胺可以回收再利用，节约原料，降低成本。