Method for producing riboflavin glucoside

一种用于生产核黄素葡糖苷的方法，其包括培养一种属于芽孢杆菌属的微生物，如短芽孢杆菌，蜡状芽孢杆菌，环状芽孢杆菌，凝结芽孢杆菌，地衣芽孢杆菌，巨大芽孢杆菌，短小芽孢杆菌或枯草芽孢杆菌，其在含有淀粉的液体培养基中在有氧条件下能产生核黄素葡糖苷。其中优选的菌株是枯草芽孢杆菌RB50∶∶〔pRF69〕60Ade+和枯草芽孢杆菌RB50∶∶〔pRF69〕60〔pRF93〕120Ade+。所产的核黄素葡糖苷可用作核黄素的溶解性更好的替代物以制备澄清饮料和注射用溶液。 A process for producing riboflavin glucoside comprises cultivating a m...

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1. Verfasser:	TATSUO HOSHINO,SETSUKO MASUDA
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE METALLURGY MICROBIOLOGY MUTATION OR GENETIC ENGINEERING PROCESSES USING MICROORGANISMS SPIRITS VINEGAR WINE
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Zusammenfassung:	一种用于生产核黄素葡糖苷的方法，其包括培养一种属于芽孢杆菌属的微生物，如短芽孢杆菌，蜡状芽孢杆菌，环状芽孢杆菌，凝结芽孢杆菌，地衣芽孢杆菌，巨大芽孢杆菌，短小芽孢杆菌或枯草芽孢杆菌，其在含有淀粉的液体培养基中在有氧条件下能产生核黄素葡糖苷。其中优选的菌株是枯草芽孢杆菌RB50∶∶〔pRF69〕60Ade+和枯草芽孢杆菌RB50∶∶〔pRF69〕60〔pRF93〕120Ade+。所产的核黄素葡糖苷可用作核黄素的溶解性更好的替代物以制备澄清饮料和注射用溶液。 A process for producing riboflavin glucoside comprises cultivating a microorganism belonging to the genus Bacillus, such as Bacillus brevis, Bacillus cereus, Bacillus circulans, Bacillus coagulans, Bacillus licheniformis, Bacillus megaterium, Bacillus pumilus or Bacillus subtilis, which is capable of producing riboflavin glucosides, in an aqueous medium containing a starch under aerobic conditions. Amongst the preferred strains are Bacillus subtilis RB50::ÄpRF69Ü60Ade+ and Bacillus subtilis RB50::ÄpRF69Ü60ÄpRF93Ü120Ade+. The so-produced riboflavin glucoside can be used as a more soluble substitute for riboflavin to prepare clear drinks and injection solutions.