Methods of reducing fat by administering benzenesulfonamide composition

The present disclosure provides a composition for reducing fat in a subject, comprising a benzenesulfonamide derivative and a pharmaceutically or cosmetically acceptable carrier thereof. Also provided is a method for fat ablation or lipolysis by administering the composition to a subject in need thereof. Further provided are methods of preventing or treating a disease or condition associated with fat accumulation by administering the composition to a subject in need thereof. 本公开提供一种用于减少受试者体内脂肪的组合物，包括苯磺酰胺衍生物及其药学上或美容上可接受的载体。还提供一种通过向有需要的受试者给药该组合物以用于脂肪消融或脂肪分解的方法。进一步提供通过向有需要的受试者给药该组合物以预防或治疗与脂肪蓄积相关的疾病或病症的方法。