Drying method of enoxaparin sodium intermediate

The invention relates to the technical field of medicines, and provides a drying method of an enoxaparin sodium intermediate, which comprises the following steps: S1, preparation: respectively dissolving heparin sodium and benzethonium chloride with water, and mixing to generate a benzethonium chloride suspension; s2, standing and settling: conveying the benzethonium chloride suspension into an overturning type filtering, washing and drying machine, and standing for 1-10 hours; s3, filtering: filtering under 0.1 to 0.7 MPa to obtain a filter cake; s4, filter cake crushing: raising the temperature to 40-70 DEG C, controlling the vacuum degree of the cavity to be-0.7 to-1.0 Mpa, and inclining to enable the filter cake on the filter plate to fall off and be crushed; s5, rotary vacuum drying: rotating the turnover type filtering, washing and drying machine at the temperature of 40-70 DEG C and the pressure of-0.7 to-1.0 Mpa, and drying a filter cake; and S6, repeating the step S5 until the total rotary vacuum dry