Synthesis method of cinacalcet hydrochloride

The invention belongs to the technical field of compounds, and discloses a cinacalcet hydrochloride synthesis method, which comprises the following steps: (1) by taking 3-trifluoromethyl phenylpropionic acid and R-naphthylethylamine as starting raw materials, carrying out heating reflux stirring reaction in an organic solvent for 24-36 hours, and after the reaction is finished, carrying out reduced pressure distillation to obtain Int.1; (2) carrying out heat preservation reaction on Int.1, the BF3-THF complex and sodium borohydride in an organic solvent for 12-16 hours, and after the reaction is finished, quenching and spin-drying to obtain a cinacalcet crude product; (3) salifying: adding the cinacalcet crude product into a solvent until the cinacalcet crude product is completely dissolved; and adding hydrochloric acid, heating to 60 DEG C, stirring for 0.5-4 hours, cooling to below 10 DEG C, preserving heat, stirring and crystallizing for 2 hours to obtain cinacalcet hydrochloride. Raw materials are wide in