Application of lemon myrtle essential oil in preparation of anti-cancer drugs

The invention discloses application of lemon myrtle essential oil in preparation of anti-cancer drugs, and belongs to the technical field of medicines. The application of the lemon myrtle essential oil in preparation of the medicine for treating the cancer is mainly attributed to the effect of the l...

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Hauptverfasser: FENG YANG, CHEN HAO, SU LIHUA, WANG YUNFEN, SUN HANG, WANG BAOQU, XU MIN
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention discloses application of lemon myrtle essential oil in preparation of anti-cancer drugs, and belongs to the technical field of medicines. The application of the lemon myrtle essential oil in preparation of the medicine for treating the cancer is mainly attributed to the effect of the lemon myrtle essential oil in remarkably inhibiting human hepatoma carcinoma cells (HepG2), human neuroblastoma carcinoma cells (SH-SY5Y), human colon cancer cells (HT-29) and human lung cancer cells (A549), and IC50 is 40.90 +/-2.23 mu g/ml, 58.60 +/-6.76 mu g/ml, 68.91 +/-4.62 mu g/ml and 57.57 +/-7.61 mu g/ml respectively. In addition, the inhibitory activity of the lemon myrtle essential oil on human hepatoma cells (HepG2) shows concentration and time dependence. A cell cycle analysis result shows that compared with a control group, HepG2 cells treated by the lemon myrtle essential oil have obvious S-phase retardation (Plt; 0.01) of the substrate; a cell apoptosis analysis result shows that the lemon myrtle esse