Bone repair scaffold material for promoting neurotization as well as preparation method and application of bone repair scaffold material

The invention discloses a bone repair scaffold material for promoting neurotization as well as a preparation method and application of the bone repair scaffold material. The preparation method comprises the following steps: firstly, preparing an nHA-Col/CS scaffold doped with nano-hydroxyapatite, collagen and chondroitin sulfate through electrostatic spinning; and assembling a plurality of basic fibroblast growth factor/collagen/chondroitin sulfate layers on the surface of the nHA-Co/CS scaffold by using a layer-by-layer self-assembly technology. The bone repair scaffold material prepared by the invention can coordinate osteogenic differentiation and neural differentiation activities of bone marrow mesenchymal stem cells, and synchronous regulation and control of osteogenesis and neurotization are beneficial to clinical treatment of critical bone defects and have good prognosis; therefore, the prepared bone repair scaffold for promoting the neurotization has relatively high application potential in the field