Composite conductive hydrogel material with simulated neural network structure and preparation method of composite conductive hydrogel material

The invention discloses a composite conductive hydrogel material with an imitated neural network structure and a preparation method of the composite conductive hydrogel material. The method comprises the following steps: 1) preparing sodium alginate fibers in a Ca < 2 + >/Mg < 2 + > coag...

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Hauptverfasser: JIN XIAOQIANG, ZHANG ZENGJIE, CHEN JIAYU, ZHAO SHENZHI, TENG-WANG SIYUAN, YAO MINJUN, YE ZHAOMING
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention discloses a composite conductive hydrogel material with an imitated neural network structure and a preparation method of the composite conductive hydrogel material. The method comprises the following steps: 1) preparing sodium alginate fibers in a Ca < 2 + >/Mg < 2 + > coagulating bath, weaving the sodium alginate fibers into a fiber web, and dipping the fiber web in an aniline/phytic acid solution to obtain a sodium alginate/polyaniline conductive fiber web; (2) carrying out surface modification on the beta-TCP by using dopamine/Tris-HCl (pH = 8.5), and adsorbing osteogenic growth promoting factors to obtain organic-inorganic hybrid nanoparticles; and 3) preparing a pre-solution by using Gelma, SilMA and ChiMA, adding the prepared organic-inorganic hybrid beta-TCP particles, and curing the sodium alginate/polyaniline conductive fiber mesh in the pre-solution to obtain the composite conductive hydrogel material with the neural network imitating structure. The material has high biocompatibility,