Method for promoting differentiation of myeloid cells into pericytes by TNFSF15 protein and application of TNFSF15 protein

The invention provides a method for promoting differentiation of myeloid cells into pericytes by TNFSF15 protein and application of the TNFSF15 protein, and belongs to the technical field of medicines. The TNFSF15 protein can protect myeloid cells, promote the increase of the myeloid cells and promo...

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Hauptverfasser: ZHANG QIANGZHE, LI LUYUAN, GU XIANGXIANG, ZHU YIPAN
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention provides a method for promoting differentiation of myeloid cells into pericytes by TNFSF15 protein and application of the TNFSF15 protein, and belongs to the technical field of medicines. The TNFSF15 protein can protect myeloid cells, promote the increase of the myeloid cells and promote the differentiation of the myeloid cells to pericytes under an in-vitro culture condition, and a new thought is provided for treating vascular diseases through pericyte therapy of exogenous administration. 本发明提供了一种TNFSF15蛋白促进髓系细胞分化为周细胞的方法及其用途,属于医药技术领域。所述TNFSF15蛋白能保护髓系细胞,促进髓系细胞的增多,并促进髓系细胞在体外培养条件下向周细胞的分化,为外源给药的周细胞疗法医治血管疾病提供新的思路。