Application of raffinose and raffinose derivative in treatment of glioblastoma

The invention relates to application of raffinose or a derivative thereof in preparation of a medicine for treating glioma diseases, and the specific mechanism is mainly as follows: the raffinose or the derivative thereof induces glioma cell senescence and promotes cell apoptosis by mediating cell c...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Hauptverfasser:	LU XIANGHE, DAI ZHANG'AN, CHEN YINGYU, GUO YUHANG, CAI LIN, ZHANG QIAN, ZHU ZHANGZHANG
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	The invention relates to application of raffinose or a derivative thereof in preparation of a medicine for treating glioma diseases, and the specific mechanism is mainly as follows: the raffinose or the derivative thereof induces glioma cell senescence and promotes cell apoptosis by mediating cell cycle G1/G2 retardation, and finally the effect of treating glioma is achieved. 本发明涉及棉子糖或其衍生物在制备用于治疗胶质瘤疾病药物中的用途，具体机制主要是棉子糖或其衍生物通过介导细胞周期G1/G2阻滞，进而诱导胶质瘤细胞衰老，促进细胞凋亡，最终达到治疗胶质瘤的作用。