Cetirizine hydrochloride oral solution and preparation method thereof

The invention provides a cetirizine hydrochloride oral solution. The cetirizine hydrochloride oral solution comprises cetirizine hydrochloride, propylene glycol, glycerol, a 70% sorbitol solution, methylparaben, propyl hydroxybenzoate, saccharin sodium salt, banana essence, glacial acetic acid and s...

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Bibliographische Detailangaben
Hauptverfasser: YE SHICHUN, ZHU JIAO, LI YULIN
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention provides a cetirizine hydrochloride oral solution. The cetirizine hydrochloride oral solution comprises cetirizine hydrochloride, propylene glycol, glycerol, a 70% sorbitol solution, methylparaben, propyl hydroxybenzoate, saccharin sodium salt, banana essence, glacial acetic acid and sodium acetate. The cetirizine hydrochloride oral solution disclosed by the invention can effectively cover the strong bitter taste of the active ingredient cetirizine hydrochloride, is convenient to take, high in stability, low in toxic and side effects, simple in preparation process, controllable in quality and low in production cost, and can be produced only by adopting conventional liquid production equipment. 本发明提供了一种盐酸西替利嗪口服溶液,所述包括盐酸西替利嗪、丙二醇、甘油、70%山梨醇溶液、羟苯甲酯、羟苯丙酯、糖精钠、香蕉香精、冰醋酸和醋酸钠。本发明的盐酸西替利嗪口服溶液,能有效掩盖了活性成分盐酸西替利嗪强烈的苦涩味道,服用方便、稳定性高、毒副作用低、制备工艺简单,质量可控,生产成本低廉,只需要采用常规的液体生产设备就能完成生产。