Novel VDAC1 inhibitors

The invention relates to compounds of general formula (I) wherein R1-7, Hy and X are as defined in claim 1. Such compounds of formula (I) bind to VDAC1 and are useful in methods of treating diabetes or prediabetes in a subject in need thereof. 本发明涉及通式(I)的化合物其中R1-7、Hy和X如权利要求1中所定义。此类式(I)的化合物结合至VDAC1并且...

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Bibliographische Detailangaben
Hauptverfasser: HANSEN KRISTIAN T, SALEHI SALEHI SEYED ALI, BROWN WESLEY D
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention relates to compounds of general formula (I) wherein R1-7, Hy and X are as defined in claim 1. Such compounds of formula (I) bind to VDAC1 and are useful in methods of treating diabetes or prediabetes in a subject in need thereof. 本发明涉及通式(I)的化合物其中R1-7、Hy和X如权利要求1中所定义。此类式(I)的化合物结合至VDAC1并且适用于治疗有需要的受试者的糖尿病或前驱糖尿病的方法中。