Dapoxetine hydrochloride orally disintegrating tablet and preparation method thereof

The invention relates to the technical field of pharmaceutical preparations, and provides a dapoxetine hydrochloride orally disintegrating tablet and a preparation method thereof. The dapoxetine hydrochloride orally disintegrating tablet is prepared from the following components in percentage by wei...

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Hauptverfasser: SHI LINGLING, QIE ZHENGGANG, WU JIE, MA XINLIANG, SUN PENG
Format: Patent
Sprache:chi ; eng
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Beschreibung
Zusammenfassung:The invention relates to the technical field of pharmaceutical preparations, and provides a dapoxetine hydrochloride orally disintegrating tablet and a preparation method thereof. The dapoxetine hydrochloride orally disintegrating tablet is prepared from the following components in percentage by weight: 13%-26% of dapoxetine hydrochloride, 73%-87% of an auxiliary material and 0.1%-1.0% of a flavoring agent, wherein the particle size D90 of the dapoxetine hydrochloride is 195-305 microns. The preparation method of the dapoxetine hydrochloride orally disintegrating tablet comprises the following steps: uniformly mixing dapoxetine hydrochloride with the auxiliary materials and the flavoring agent, and tabletting to obtain the dapoxetine hydrochloride orally disintegrating tablet. Through the technical scheme, the problems of slow release, poor stability and poor reproducibility of a dapoxetine hydrochloride preparation in the prior art are solved. 本发明涉及药物制剂技术领域,提出了一种盐酸达泊西汀口崩片及其制备方法。所述盐酸达泊西汀口崩片由以下重量百分比的组分组成:盐酸达泊西