Cyclosporine eye drops and preparation method thereof

The invention discloses cyclosporine eye drops, which are prepared from the following raw material components in percentage by mass: 0.05 to 0.1 percent of cyclosporine; 1-2.5% of an oil phase; 0.8 to 2.0 percent of polysorbate 80; 2-3% of glycerol; 0.05 to 1.4 percent of a biological adhesion material; and sodium hydroxide and purified water. According to the cyclosporine sustained-release preparation, cyclosporine can be stably released, the retention time of the medicine in eyes is prolonged, the distribution of the medicine in eye tissues is increased, and the medicine effect is improved. 本发明公开了一种环孢素滴眼液，其原料包括如下质量百分比的组分：环孢素0.05～0.1％；油相1～2.5％；聚山梨酯80 0.8～2.0％；甘油2～3％；生物黏附材料0.05～1.4％；以及氢氧化钠和纯化水。本发明能够使环孢素平稳释放，延长药物在眼内滞留时间，增加药物的眼组织的分布，提高药效。