Engineered mesenchymal stem cell bionic flexible lipidosome for specifically targeting lung inflammation tissue as well as preparation method and application of engineered mesenchymal stem cell bionic flexible lipidosome

The invention discloses an engineered mesenchymal stem cell bionic flexible liposome for specifically targeting lung inflammation tissues as well as a preparation method and application of the engineered mesenchymal stem cell bionic flexible liposome, and relates to the field of drug targeting delivery systems. By means of the stem cell membrane modified through genetic engineering, targeting to vascular endothelial cells of lung inflammation tissue can be achieved firstly, then targeting to inflammation lung epithelial cells is further achieved, and more efficient and more accurate targeting capacity is achieved. The sequential double-targeting design can ensure accurate targeted delivery of the anti-inflammatory drug, improve the curative effect of the anti-inflammatory drug, reduce the use dosage of the anti-inflammatory drug and reduce toxic and side effects, and is expected to meet the clinical requirements on targeted therapy of lung inflammation. The engineered mesenchymal stem cell bionic flexible lip