Salvianolic acid A carbomer gel and application thereof

The invention relates to the field of external medicines, in particular to a salvianolic acid A carbomer gel and application thereof. The salvianolic acid A and carbomer gel is prepared from salvianolic acid A as an effective component and vitamin C, ethanol, glycerol, carbomer 940, triethanolamine...

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Hauptverfasser: ZUO ZHENQI, GUO WENJIE, XU QIANG, HE YINGXUE
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention relates to the field of external medicines, in particular to a salvianolic acid A carbomer gel and application thereof. The salvianolic acid A and carbomer gel is prepared from salvianolic acid A as an effective component and vitamin C, ethanol, glycerol, carbomer 940, triethanolamine and deionized water in a matrix according to a certain proportion, wherein the vitamin C, the ethanol, the glycerol, the carbomer 940, the triethanolamine and the deionized water are contained in the matrix. The salvianolic acid A carbomer gel prepared by the invention is faint yellow, glittering and transparent, appropriate in viscosity and good in stability. Pharmacodynamic studies show that the salvianolic acid A carbomer gel disclosed by the invention has a good treatment effect on an imiquimod-induced mouse psoriasis-like disease model, shows obvious advantages compared with other administration modes, and is non-irritant to skin. 本发明涉及外用药物领域,涉及一种丹酚酸A卡波姆凝胶剂及其应用。丹酚酸A卡波姆凝胶剂由有效成分丹酚酸A和基质中的维生素C、乙醇、甘油、卡波姆940、三乙醇胺、去离