IncRNA and application of antisense oligonucleotide thereof
The invention discloses lncRNA (long non-coding ribonucleic acid) and application of antisense oligonucleotide of the lncRNA. The lncRNA is lncRNA 857.1, and the nucleotide sequence of the lncRNA is shown as SEQ ID NO. 1. The nucleotide sequence of the antisense oligonucleotide is selected from SEQ...
Gespeichert in:
| Hauptverfasser: | , , , , , |
|---|---|
| Format: | Patent |
| Sprache: | chi ; eng |
| Schlagworte: | |
| Online-Zugang: | Volltext bestellen |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | |
| container_start_page | |
| container_title | |
| container_volume | |
| creator | PU SHIQI QU QINGSHENG FANG YUJIA QIAN PING XU MEI TANG XUDONG |
| description | The invention discloses lncRNA (long non-coding ribonucleic acid) and application of antisense oligonucleotide of the lncRNA. The lncRNA is lncRNA 857.1, and the nucleotide sequence of the lncRNA is shown as SEQ ID NO. 1. The nucleotide sequence of the antisense oligonucleotide is selected from SEQ ID NO.2 to 3. The antisense oligonucleotide targeting lncRNA857.1 disclosed by the invention can effectively inhibit proliferation of nosema bombycis, and has a remarkable effect in preparation of RNAi medicines for preventing or treating diseases caused by nosema bombycis infection.
本发明公开了一种lncRNA及其反义寡核苷酸的应用，所述lncRNA为lncRNA857.1，其核苷酸序列如SEQ ID NO.1所示。所述反义寡核苷酸的核苷酸序列选自SEQ IDNO.2～3。本发明公开的靶向lncRNA857.1的反义寡核苷酸可有效抑制家蚕微孢子虫增殖，用于制备预防或治疗由家蚕微孢子虫感染引起的疾病的RNAi药物中效果显著。 |
| format | Patent |
| fullrecord | <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_CN116121253A</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>CN116121253A</sourcerecordid><originalsourceid>FETCH-epo_espacenet_CN116121253A3</originalsourceid><addsrcrecordid>eNrjZLD2zEsO8nNUSMxLUUgsKMjJTE4syczPU8hPAwqVZBan5hWnKuTnZKbn55Um56Tml2SmpCqUZKQWpean8TCwpiXmFKfyQmluBkU31xBnD93Ugvz41OKCxOTUvNSSeGc_Q0MzQyNDI1NjR2Ni1AAAniYvYg</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>IncRNA and application of antisense oligonucleotide thereof</title><source>esp@cenet</source><creator>PU SHIQI ; QU QINGSHENG ; FANG YUJIA ; QIAN PING ; XU MEI ; TANG XUDONG</creator><creatorcontrib>PU SHIQI ; QU QINGSHENG ; FANG YUJIA ; QIAN PING ; XU MEI ; TANG XUDONG</creatorcontrib><description>The invention discloses lncRNA (long non-coding ribonucleic acid) and application of antisense oligonucleotide of the lncRNA. The lncRNA is lncRNA 857.1, and the nucleotide sequence of the lncRNA is shown as SEQ ID NO. 1. The nucleotide sequence of the antisense oligonucleotide is selected from SEQ ID NO.2 to 3. The antisense oligonucleotide targeting lncRNA857.1 disclosed by the invention can effectively inhibit proliferation of nosema bombycis, and has a remarkable effect in preparation of RNAi medicines for preventing or treating diseases caused by nosema bombycis infection.
本发明公开了一种lncRNA及其反义寡核苷酸的应用，所述lncRNA为lncRNA857.1，其核苷酸序列如SEQ ID NO.1所示。所述反义寡核苷酸的核苷酸序列选自SEQ IDNO.2～3。本发明公开的靶向lncRNA857.1的反义寡核苷酸可有效抑制家蚕微孢子虫增殖，用于制备预防或治疗由家蚕微孢子虫感染引起的疾病的RNAi药物中效果显著。</description><language>chi ; eng</language><subject>AGRICULTURE ; ANIMAL HUSBANDRY ; BEER ; BIOCHEMISTRY ; CARE OF BIRDS, FISHES, INSECTS ; CHEMISTRY ; COMPOSITIONS THEREOF ; CULTURE MEDIA ; ENZYMOLOGY ; FISHING ; FORESTRY ; HUMAN NECESSITIES ; HUNTING ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; MICROBIOLOGY ; MICROORGANISMS OR ENZYMES ; MUTATION OR GENETIC ENGINEERING ; NEW BREEDS OF ANIMALS ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS ; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS ; SPIRITS ; TRAPPING ; VINEGAR ; WINE</subject><creationdate>2023</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20230516&DB=EPODOC&CC=CN&NR=116121253A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20230516&DB=EPODOC&CC=CN&NR=116121253A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>PU SHIQI</creatorcontrib><creatorcontrib>QU QINGSHENG</creatorcontrib><creatorcontrib>FANG YUJIA</creatorcontrib><creatorcontrib>QIAN PING</creatorcontrib><creatorcontrib>XU MEI</creatorcontrib><creatorcontrib>TANG XUDONG</creatorcontrib><title>IncRNA and application of antisense oligonucleotide thereof</title><description>The invention discloses lncRNA (long non-coding ribonucleic acid) and application of antisense oligonucleotide of the lncRNA. The lncRNA is lncRNA 857.1, and the nucleotide sequence of the lncRNA is shown as SEQ ID NO. 1. The nucleotide sequence of the antisense oligonucleotide is selected from SEQ ID NO.2 to 3. The antisense oligonucleotide targeting lncRNA857.1 disclosed by the invention can effectively inhibit proliferation of nosema bombycis, and has a remarkable effect in preparation of RNAi medicines for preventing or treating diseases caused by nosema bombycis infection.
本发明公开了一种lncRNA及其反义寡核苷酸的应用，所述lncRNA为lncRNA857.1，其核苷酸序列如SEQ ID NO.1所示。所述反义寡核苷酸的核苷酸序列选自SEQ IDNO.2～3。本发明公开的靶向lncRNA857.1的反义寡核苷酸可有效抑制家蚕微孢子虫增殖，用于制备预防或治疗由家蚕微孢子虫感染引起的疾病的RNAi药物中效果显著。</description><subject>AGRICULTURE</subject><subject>ANIMAL HUSBANDRY</subject><subject>BEER</subject><subject>BIOCHEMISTRY</subject><subject>CARE OF BIRDS, FISHES, INSECTS</subject><subject>CHEMISTRY</subject><subject>COMPOSITIONS THEREOF</subject><subject>CULTURE MEDIA</subject><subject>ENZYMOLOGY</subject><subject>FISHING</subject><subject>FORESTRY</subject><subject>HUMAN NECESSITIES</subject><subject>HUNTING</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>MICROBIOLOGY</subject><subject>MICROORGANISMS OR ENZYMES</subject><subject>MUTATION OR GENETIC ENGINEERING</subject><subject>NEW BREEDS OF ANIMALS</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</subject><subject>REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><subject>SPIRITS</subject><subject>TRAPPING</subject><subject>VINEGAR</subject><subject>WINE</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2023</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZLD2zEsO8nNUSMxLUUgsKMjJTE4syczPU8hPAwqVZBan5hWnKuTnZKbn55Um56Tml2SmpCqUZKQWpean8TCwpiXmFKfyQmluBkU31xBnD93Ugvz41OKCxOTUvNSSeGc_Q0MzQyNDI1NjR2Ni1AAAniYvYg</recordid><startdate>20230516</startdate><enddate>20230516</enddate><creator>PU SHIQI</creator><creator>QU QINGSHENG</creator><creator>FANG YUJIA</creator><creator>QIAN PING</creator><creator>XU MEI</creator><creator>TANG XUDONG</creator><scope>EVB</scope></search><sort><creationdate>20230516</creationdate><title>IncRNA and application of antisense oligonucleotide thereof</title><author>PU SHIQI ; QU QINGSHENG ; FANG YUJIA ; QIAN PING ; XU MEI ; TANG XUDONG</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CN116121253A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>chi ; eng</language><creationdate>2023</creationdate><topic>AGRICULTURE</topic><topic>ANIMAL HUSBANDRY</topic><topic>BEER</topic><topic>BIOCHEMISTRY</topic><topic>CARE OF BIRDS, FISHES, INSECTS</topic><topic>CHEMISTRY</topic><topic>COMPOSITIONS THEREOF</topic><topic>CULTURE MEDIA</topic><topic>ENZYMOLOGY</topic><topic>FISHING</topic><topic>FORESTRY</topic><topic>HUMAN NECESSITIES</topic><topic>HUNTING</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>MICROBIOLOGY</topic><topic>MICROORGANISMS OR ENZYMES</topic><topic>MUTATION OR GENETIC ENGINEERING</topic><topic>NEW BREEDS OF ANIMALS</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</topic><topic>REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><topic>SPIRITS</topic><topic>TRAPPING</topic><topic>VINEGAR</topic><topic>WINE</topic><toplevel>online_resources</toplevel><creatorcontrib>PU SHIQI</creatorcontrib><creatorcontrib>QU QINGSHENG</creatorcontrib><creatorcontrib>FANG YUJIA</creatorcontrib><creatorcontrib>QIAN PING</creatorcontrib><creatorcontrib>XU MEI</creatorcontrib><creatorcontrib>TANG XUDONG</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>PU SHIQI</au><au>QU QINGSHENG</au><au>FANG YUJIA</au><au>QIAN PING</au><au>XU MEI</au><au>TANG XUDONG</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>IncRNA and application of antisense oligonucleotide thereof</title><date>2023-05-16</date><risdate>2023</risdate><abstract>The invention discloses lncRNA (long non-coding ribonucleic acid) and application of antisense oligonucleotide of the lncRNA. The lncRNA is lncRNA 857.1, and the nucleotide sequence of the lncRNA is shown as SEQ ID NO. 1. The nucleotide sequence of the antisense oligonucleotide is selected from SEQ ID NO.2 to 3. The antisense oligonucleotide targeting lncRNA857.1 disclosed by the invention can effectively inhibit proliferation of nosema bombycis, and has a remarkable effect in preparation of RNAi medicines for preventing or treating diseases caused by nosema bombycis infection.
本发明公开了一种lncRNA及其反义寡核苷酸的应用，所述lncRNA为lncRNA857.1，其核苷酸序列如SEQ ID NO.1所示。所述反义寡核苷酸的核苷酸序列选自SEQ IDNO.2～3。本发明公开的靶向lncRNA857.1的反义寡核苷酸可有效抑制家蚕微孢子虫增殖，用于制备预防或治疗由家蚕微孢子虫感染引起的疾病的RNAi药物中效果显著。</abstract><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext_linktorsrc |
| identifier | |
| ispartof | |
| issn | |
| language | chi ; eng |
| recordid | cdi_epo_espacenet_CN116121253A |
| source | esp@cenet |
| subjects | AGRICULTURE ANIMAL HUSBANDRY BEER BIOCHEMISTRY CARE OF BIRDS, FISHES, INSECTS CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY FISHING FORESTRY HUMAN NECESSITIES HUNTING HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING NEW BREEDS OF ANIMALS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS TRAPPING VINEGAR WINE |
| title | IncRNA and application of antisense oligonucleotide thereof |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-04T07%3A39%3A12IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=PU%20SHIQI&rft.date=2023-05-16&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3ECN116121253A%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |