Method and system for forming dosage form within package

A method and system for forming a pharmaceutical dosage form within a portion of a blister package. The method includes the step of providing a blister package for a dosage form having a recess. A predetermined amount of a drug-containing powder material comprising drug-containing particles is deposited into a substantially homogeneous powder layer within the recess. A bonding liquid is then deposited in a pattern on the powder layer within the recesses to bond particles of the powder layer and form an incremental wetting layer. Excess solvent in the bond material may be removed to form an incremental bond layer. These steps are repeated in sequence at least one or more times to form the pharmaceutical dosage form within the blister pack. 一种在泡罩包装的一部分内形成药物剂型的方法和系统。该方法包括提供具有凹部的用于剂型的泡罩包装的步骤。将预定量的包含含药颗粒的含药粉末材料沉积成凹部内的基本均匀的粉末层。然后在凹部内的粉末层上以一图案形式沉积粘结液体，以粘结粉末层的颗粒并形成增量润湿层。可以去除粘结材料中多余的溶剂以形成增量粘结层。依次重复这些步骤至少一次或多次，以在泡罩包装内形成药物剂型。