MRNA (messenger Ribonucleic Acid) for coding chicken infectious bursal disease virus antigen and mRNA vaccine thereof
The invention provides mRNA (messenger Ribonucleic Acid) for coding an infectious bursal disease virus antigen and an mRNA vaccine thereof. The mRNA at least contains at least one protein for coding the infectious bursal disease virus and/or a coding region of a fragment of at least one protein. The...
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| creator | JIANG JIANHAO HE ZHAOMING ZHONG TIANYI TAN XIANG HU HONGPENG WEI SHANMING ZHAO LIXIANG GENG YICHENG CAO QINGQING YI CHENG ZHANG FAN |
| description | The invention provides mRNA (messenger Ribonucleic Acid) for coding an infectious bursal disease virus antigen and an mRNA vaccine thereof. The mRNA at least contains at least one protein for coding the infectious bursal disease virus and/or a coding region of a fragment of at least one protein. The mRNA for coding the infectious bursal disease virus antigen is higher in production speed, more flexible and lower in cost, and cannot be integrated into a host genome, so that the basic safety is ensured. Meanwhile, the invention also discloses application of the mRNA for coding the infectious bursal disease virus antigen to preparation of the mRNA vaccine for preventing the infectious bursal disease and the mRNA vaccine, and compared with production of other complex vaccines, the vaccine disclosed by the invention is fast in reaction time and low in pollution risk.
本发明提供了一种编码鸡传染性法氏囊病病毒抗原的mRNA及其mRNA疫苗，所述mRNA至少含有编码鸡传染性法氏囊病病毒的至少一个蛋白，和/或至少一个蛋白的片段的编码区。本发明的编码鸡传染性法氏囊病病毒抗原的mRNA生产速度更快、更灵活、成本更低，不会被整合到宿主基因组中，保证了基本的安全性。同时，本 |
| format | Patent |
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本发明提供了一种编码鸡传染性法氏囊病病毒抗原的mRNA及其mRNA疫苗，所述mRNA至少含有编码鸡传染性法氏囊病病毒的至少一个蛋白，和/或至少一个蛋白的片段的编码区。本发明的编码鸡传染性法氏囊病病毒抗原的mRNA生产速度更快、更灵活、成本更低，不会被整合到宿主基因组中，保证了基本的安全性。同时，本</description><language>chi ; eng</language><subject>BEER ; BIOCHEMISTRY ; CHEMISTRY ; COMPOSITIONS THEREOF ; CULTURE MEDIA ; ENZYMOLOGY ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; MICROBIOLOGY ; MICROORGANISMS OR ENZYMES ; MUTATION OR GENETIC ENGINEERING ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS ; SPIRITS ; VINEGAR ; WINE</subject><creationdate>2023</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20230512&DB=EPODOC&CC=CN&NR=116103319A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20230512&DB=EPODOC&CC=CN&NR=116103319A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>JIANG JIANHAO</creatorcontrib><creatorcontrib>HE ZHAOMING</creatorcontrib><creatorcontrib>ZHONG TIANYI</creatorcontrib><creatorcontrib>TAN XIANG</creatorcontrib><creatorcontrib>HU HONGPENG</creatorcontrib><creatorcontrib>WEI SHANMING</creatorcontrib><creatorcontrib>ZHAO LIXIANG</creatorcontrib><creatorcontrib>GENG YICHENG</creatorcontrib><creatorcontrib>CAO QINGQING</creatorcontrib><creatorcontrib>YI CHENG</creatorcontrib><creatorcontrib>ZHANG FAN</creatorcontrib><title>MRNA (messenger Ribonucleic Acid) for coding chicken infectious bursal disease virus antigen and mRNA vaccine thereof</title><description>The invention provides mRNA (messenger Ribonucleic Acid) for coding an infectious bursal disease virus antigen and an mRNA vaccine thereof. The mRNA at least contains at least one protein for coding the infectious bursal disease virus and/or a coding region of a fragment of at least one protein. The mRNA for coding the infectious bursal disease virus antigen is higher in production speed, more flexible and lower in cost, and cannot be integrated into a host genome, so that the basic safety is ensured. Meanwhile, the invention also discloses application of the mRNA for coding the infectious bursal disease virus antigen to preparation of the mRNA vaccine for preventing the infectious bursal disease and the mRNA vaccine, and compared with production of other complex vaccines, the vaccine disclosed by the invention is fast in reaction time and low in pollution risk.
本发明提供了一种编码鸡传染性法氏囊病病毒抗原的mRNA及其mRNA疫苗，所述mRNA至少含有编码鸡传染性法氏囊病病毒的至少一个蛋白，和/或至少一个蛋白的片段的编码区。本发明的编码鸡传染性法氏囊病病毒抗原的mRNA生产速度更快、更灵活、成本更低，不会被整合到宿主基因组中，保证了基本的安全性。同时，本</description><subject>BEER</subject><subject>BIOCHEMISTRY</subject><subject>CHEMISTRY</subject><subject>COMPOSITIONS THEREOF</subject><subject>CULTURE MEDIA</subject><subject>ENZYMOLOGY</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>MICROBIOLOGY</subject><subject>MICROORGANISMS OR ENZYMES</subject><subject>MUTATION OR GENETIC ENGINEERING</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><subject>SPIRITS</subject><subject>VINEGAR</subject><subject>WINE</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2023</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNjbsKwkAQANNYiPoPa6eF4BEQLENQbEwR7MNlby9ZTPbCPfL9RvADrAaGgVln6VlXBRxGCoGkIw81t04SDsQIBbI5gnUe0BmWDrBnfJMAiyWM7FKANvmgBzAcSAeCmf0itUTulk6LgfE7mDUiC0HsyZOz22xl9RBo9-Mm299vr_Jxosk1FCaNJBSbslLqos55rq5F_k_zAQFwQ-w</recordid><startdate>20230512</startdate><enddate>20230512</enddate><creator>JIANG JIANHAO</creator><creator>HE ZHAOMING</creator><creator>ZHONG TIANYI</creator><creator>TAN XIANG</creator><creator>HU HONGPENG</creator><creator>WEI SHANMING</creator><creator>ZHAO LIXIANG</creator><creator>GENG YICHENG</creator><creator>CAO QINGQING</creator><creator>YI CHENG</creator><creator>ZHANG FAN</creator><scope>EVB</scope></search><sort><creationdate>20230512</creationdate><title>MRNA (messenger Ribonucleic Acid) for coding chicken infectious bursal disease virus antigen and mRNA vaccine thereof</title><author>JIANG JIANHAO ; HE ZHAOMING ; ZHONG TIANYI ; TAN XIANG ; HU HONGPENG ; WEI SHANMING ; ZHAO LIXIANG ; GENG YICHENG ; CAO QINGQING ; YI CHENG ; ZHANG FAN</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CN116103319A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>chi ; eng</language><creationdate>2023</creationdate><topic>BEER</topic><topic>BIOCHEMISTRY</topic><topic>CHEMISTRY</topic><topic>COMPOSITIONS THEREOF</topic><topic>CULTURE MEDIA</topic><topic>ENZYMOLOGY</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>MICROBIOLOGY</topic><topic>MICROORGANISMS OR ENZYMES</topic><topic>MUTATION OR GENETIC ENGINEERING</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><topic>SPIRITS</topic><topic>VINEGAR</topic><topic>WINE</topic><toplevel>online_resources</toplevel><creatorcontrib>JIANG JIANHAO</creatorcontrib><creatorcontrib>HE ZHAOMING</creatorcontrib><creatorcontrib>ZHONG TIANYI</creatorcontrib><creatorcontrib>TAN XIANG</creatorcontrib><creatorcontrib>HU HONGPENG</creatorcontrib><creatorcontrib>WEI SHANMING</creatorcontrib><creatorcontrib>ZHAO LIXIANG</creatorcontrib><creatorcontrib>GENG YICHENG</creatorcontrib><creatorcontrib>CAO QINGQING</creatorcontrib><creatorcontrib>YI CHENG</creatorcontrib><creatorcontrib>ZHANG FAN</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>JIANG JIANHAO</au><au>HE ZHAOMING</au><au>ZHONG TIANYI</au><au>TAN XIANG</au><au>HU HONGPENG</au><au>WEI SHANMING</au><au>ZHAO LIXIANG</au><au>GENG YICHENG</au><au>CAO QINGQING</au><au>YI CHENG</au><au>ZHANG FAN</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>MRNA (messenger Ribonucleic Acid) for coding chicken infectious bursal disease virus antigen and mRNA vaccine thereof</title><date>2023-05-12</date><risdate>2023</risdate><abstract>The invention provides mRNA (messenger Ribonucleic Acid) for coding an infectious bursal disease virus antigen and an mRNA vaccine thereof. The mRNA at least contains at least one protein for coding the infectious bursal disease virus and/or a coding region of a fragment of at least one protein. The mRNA for coding the infectious bursal disease virus antigen is higher in production speed, more flexible and lower in cost, and cannot be integrated into a host genome, so that the basic safety is ensured. Meanwhile, the invention also discloses application of the mRNA for coding the infectious bursal disease virus antigen to preparation of the mRNA vaccine for preventing the infectious bursal disease and the mRNA vaccine, and compared with production of other complex vaccines, the vaccine disclosed by the invention is fast in reaction time and low in pollution risk.
本发明提供了一种编码鸡传染性法氏囊病病毒抗原的mRNA及其mRNA疫苗，所述mRNA至少含有编码鸡传染性法氏囊病病毒的至少一个蛋白，和/或至少一个蛋白的片段的编码区。本发明的编码鸡传染性法氏囊病病毒抗原的mRNA生产速度更快、更灵活、成本更低，不会被整合到宿主基因组中，保证了基本的安全性。同时，本</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE |
| title | MRNA (messenger Ribonucleic Acid) for coding chicken infectious bursal disease virus antigen and mRNA vaccine thereof |
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