Engineered microorganisms for improved pentose fermentation

Described herein are recombinant host organisms having an active pentose fermentation pathway and further comprising a heterologous polynucleotide encoding a non-phosphorylated NADP-dependent glyceraldehyde-3-phosphate dehydrogenase (GAPN). Also described are methods of using these recombinant host...

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Hauptverfasser: TASSONE MONICA, ALLAIN EMMANUELLE
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:Described herein are recombinant host organisms having an active pentose fermentation pathway and further comprising a heterologous polynucleotide encoding a non-phosphorylated NADP-dependent glyceraldehyde-3-phosphate dehydrogenase (GAPN). Also described are methods of using these recombinant host organisms to produce fermentation products, such as ethanol, from starch-containing or cellulose-containing materials. 本文描述了重组宿主生物,其具有活性戊糖发酵途径并且进一步包含编码非磷酸化NADP依赖性甘油醛-3-磷酸脱氢酶(GAPN)的异源多核苷酸。还描述了用这些重组宿主生物从含淀粉材料或含纤维素材料生产发酵产物例如乙醇的方法。