Method for detecting multiple components in liver-strengthening capsule based on high-resolution liquid chromatography-mass spectrometry

The invention relates to a method for detecting multiple components in a liver-strengthening capsule based on a high-resolution liquid chromatography-mass spectrometry technology. The method comprises the following steps: taking a sample capsule content, precisely weighing, mixing with a solvent, carrying out vortex treatment, carrying out ultrasonic treatment, centrifuging, uniformly shaking, filtering, and taking a subsequent filtrate to obtain a sample to be detected; a sample to be detected is subjected to UHPLC-QTOF-MS/MS detection, a stationary phase of a high performance liquid phase is a C18 column, a mobile phase A is a 0.1% formic acid aqueous solution containing 1-3mM ammonium acetate, a mobile phase B is acetonitrile, gradient elution is adopted, the flow velocity is 0.1-1.0 mL/min, the column temperature is 20-40 DEG C, a positive ion mode and a negative ion mode are adopted in mass spectrometry, an electrospray ion source is adopted, and the scanning mode is a full scanning/data dependent second