Application of serum miRNA in auxiliary diagnosis of cognitive impairment after cerebral apoplexy

The invention belongs to the technical field of biological diagnosis, and discloses a miRNA marker for auxiliary diagnosis of cognitive impairment after cerebral apoplexy, and the miRNA marker is characterized in that miRNA is selected from at least one of the following groups: miRNA-34, miRNA-21 an...

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Bibliographische Detailangaben
Hauptverfasser: MOU YANG, HUANG LIN, LI YAMEI, FENG RONGJIAN, YU QIAN, ZHANG JING
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention belongs to the technical field of biological diagnosis, and discloses a miRNA marker for auxiliary diagnosis of cognitive impairment after cerebral apoplexy, and the miRNA marker is characterized in that miRNA is selected from at least one of the following groups: miRNA-34, miRNA-21 and miRNA-135. Several novel miRNA markers for auxiliary diagnosis of cognitive impairment after cerebral apoplexy are found, and the miRNA markers have the advantages of being easy to detect, economical, high in sensitivity and the like, and have potential clinical application value. 本发明属于生物学诊断技术领域,公开了一种辅助诊断脑卒中后认知障碍的miRNA标志物,其特征在于,所述miRNA选自以下组中的至少一种:miRNA-34、miRNA-21、miRNA-135。本发明发现了几种新的辅助诊断脑卒中后认知障碍的miRNA标志物,该miRNA标志物具有易于检测、经济、灵敏性高等优点,具有潜在的临床应用价值。