Synthetic method of ethyl trifluoroacetoacetate

The invention belongs to the technical field of chemical synthesis, and particularly relates to a synthetic method of ethyl trifluoroacetoacetate. According to the invention, trifluoroacetic acid is used as a raw material, an esterification reaction is carried out, an intermediate ethyl trifluoroace...

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Hauptverfasser: JIN LUYI, CHEN JIANLONG
Format: Patent
Sprache:chi ; eng
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Beschreibung
Zusammenfassung:The invention belongs to the technical field of chemical synthesis, and particularly relates to a synthetic method of ethyl trifluoroacetoacetate. According to the invention, trifluoroacetic acid is used as a raw material, an esterification reaction is carried out, an intermediate ethyl trifluoroacetate is synthesized, then a Claisen condensation reaction is carried out, and ethyl trifluoroacetoacetate is effectively synthesized, so that the synthesis yield and yield are improved. 本发明属于化学合成技术领域,具体涉及一种三氟乙酰乙酸乙酯的合成方法。本发明以三氟乙酸作为原料,通过酯化反应,合成中间体三氟乙酸乙酯,再进行克莱森缩合反应,有效合成三氟乙酰乙酸乙酯,从而提高了合成的产率和收率。