Spiro-containing derivative, and preparation method and application thereof

Spiro-containing derivative, and preparation method and application thereof

The invention belongs to the field of medical treatment, and particularly relates to a spiro-containing derivative as well as a preparation method and application thereof. Particularly, the invention relates to a compound shown in a general formula (I), a preparation method of the compound, a pharma...

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Hauptverfasser: ZOU YUANHAI, QIN JUN, WU YONGQI, JIANG XINJIAN, HU ZHIJING, FENG JIAQUAN, WAN ZEHONG, ZHOU BINGCHENG, HUANG WEI
Format: Patent
Sprache:chi ; eng
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CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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creator ZOU YUANHAI
QIN JUN
WU YONGQI
JIANG XINJIAN
HU ZHIJING
FENG JIAQUAN
WAN ZEHONG
ZHOU BINGCHENG
HUANG WEI
description The invention belongs to the field of medical treatment, and particularly relates to a spiro-containing derivative as well as a preparation method and application thereof. Particularly, the invention relates to a compound shown in a general formula (I), a preparation method of the compound, a pharmaceutical composition containing the compound and application of the compound in preparation of drugs for preventing and/or treating central nervous system diseases related to 5-hydroxytryptamine receptors and/or trace amine related receptors and/or dopamine receptors of mammals. 本发明属于医疗领域，具体涉及含螺环类衍生物、其制备方法和应用。特别地，本发明涉及通式(I)所示的化合物、其制备方法及含有该化合物的药物组合物，及其在制备预防和/或治疗与哺乳动物5-羟色胺受体和/或痕量胺相关受体和/或多巴胺受体相关的中枢神经系统疾病药物中的应用。
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
title Spiro-containing derivative, and preparation method and application thereof
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