Spiro-containing derivative, and preparation method and application thereof

The invention belongs to the field of medical treatment, and particularly relates to a spiro-containing derivative as well as a preparation method and application thereof. Particularly, the invention relates to a compound shown in a general formula (I), a preparation method of the compound, a pharma...

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Bibliographische Detailangaben
Hauptverfasser: ZOU YUANHAI, QIN JUN, WU YONGQI, JIANG XINJIAN, HU ZHIJING, FENG JIAQUAN, WAN ZEHONG, ZHOU BINGCHENG, HUANG WEI
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention belongs to the field of medical treatment, and particularly relates to a spiro-containing derivative as well as a preparation method and application thereof. Particularly, the invention relates to a compound shown in a general formula (I), a preparation method of the compound, a pharmaceutical composition containing the compound and application of the compound in preparation of drugs for preventing and/or treating central nervous system diseases related to 5-hydroxytryptamine receptors and/or trace amine related receptors and/or dopamine receptors of mammals. 本发明属于医疗领域,具体涉及含螺环类衍生物、其制备方法和应用。特别地,本发明涉及通式(I)所示的化合物、其制备方法及含有该化合物的药物组合物,及其在制备预防和/或治疗与哺乳动物5-羟色胺受体和/或痕量胺相关受体和/或多巴胺受体相关的中枢神经系统疾病药物中的应用。