N-substituted fluorine-containing piperidine derivative as well as preparation method and application thereof

The invention provides a compound as shown in a formula (I) or (II) or a stereoisomer or pharmaceutically acceptable salt thereof, and also provides a preparation method and application of the N-substituted fluorine-containing piperidine derivative, and the compound has an inhibition effect on fungi...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: ZHU LINGUI, LIU JINGZHOU, YU FENG, LU SHOUFU
Format: Patent
Sprache:chi ; eng
Schlagworte:
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:The invention provides a compound as shown in a formula (I) or (II) or a stereoisomer or pharmaceutically acceptable salt thereof, and also provides a preparation method and application of the N-substituted fluorine-containing piperidine derivative, and the compound has an inhibition effect on fungi such as trichophyton rubrum, trichophyton mentagrophytes and candida albicans. 本发明提供了一种式(Ⅰ)或(Ⅱ)所示化合物或其立体异构体或其药学上可接受的盐,本发明还提供了所述含N-取代含氟哌啶衍生物的制备方法以及应用,所述的化合物对红色毛癣菌、须癣毛癣菌和白色念珠菌等真菌具有抑制作用。