Preparation method of resorcinol ester derivative with tyrosinase inhibitory activity

The invention provides a preparation method of a resorcinol ester derivative with tyrosinase inhibitory activity, and relates to the technical field of preparation of resorcinol ester derivatives. The preparation method of the resorcinol ester derivative with tyrosinase inhibitory activity specifically comprises the following steps: S1, synthesis of compounds 1-5; S2, synthesis of compounds 6-10; S3, determination of the inhibition rate of the compounds 1-10 on tyrosinase activity; and S4, molecular docking of the compounds 1-5 and tyrosinase. The method comprises the following steps: synthesizing a p-resorcinol ester derivative in one step, reacting resorcinol with corresponding acyl chloride under the catalysis of triethylamine by taking dichloromethane as a solvent to obtain a crude product, removing the solvent from the reaction liquid after the reaction is finished, extracting, concentrating to obtain a crude product, and separating and purifying by column chromatography to obtain a target compound. Comp